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NEDD4-2 抗体 (AA 275-325)
This anti-NEDD4-2 antibody is a 兔 多克隆 antibody detecting NEDD4-2 in IHC. Suitable for 人 和 小鼠.
Quick Overview for NEDD4-2 抗体 (AA 275-325) (ABIN7448685)
抗原
See all NEDD4-2 (NEDD4L) 抗体
NEDD4-2 (NEDD4L)
(E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
适用
All reactivities for NEDD4-2 抗体
人, 小鼠
宿主
All hosts for NEDD4-2 抗体
兔
克隆类型
All clonalities for NEDD4-2 抗体
多克隆
标记
All conjugates for NEDD4-2 抗体
This NEDD4-2 antibody is un-conjugated
应用范围
All applications for NEDD4-2 抗体
Immunohistochemistry (IHC)
NEDD4-2抗体详情
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抗原表位
All epitopes for NEDD4-2 抗体
AA 275-325
原理
Rabbit anti-NEDD4L IHC Antibody, Affinity Purified
预测反应
Rat,Bovine,Dog,Horse,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Naked mole rat,African elephant,White-tufted-ear marmoset,Zebra finch,Crab-eating macaque
纯化方法
Affinity Purified
免疫原
Between AA 275 and 325
亚型
IgG
Alternatives
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anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 275-325) antibody
NEDD4L
适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig
WB, IHC, IF, IP, IHC (p)
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
1:100 - 1:500
限制
仅限研究用
贮存及处理
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浓度
250 μg/mL
缓冲液
Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
有效期
12 months
NEDD4-2目标详情
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抗原
NEDD4-2 (NEDD4L)
(E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
别名
NEDD4L
背景
Background: NEDD4L (neural precursor cell expressed, developmentally down-regulated 4-like) functions as an E3 ubiquitin-protein ligase. NEDD4L inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. It also promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5 [taken from the Universal Protein Resource (UniProt) wwwuniprotorg/uniprot/Q96PU5].
基因ID
23327
NCBI登录号
NP_001138439
UniProt
Q96PU5
途径
Negative Regulation of Transporter Activity
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原发性抗体
anti-NEDD4-2 抗体 (AA 275-325) (ABIN7448685)
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