APC 抗体 (AA 1-50)
Our Local Distributor
北京 101111
Quick Overview for APC 抗体 (AA 1-50) (ABIN7448412)
抗原
See all APC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-50
-
原理
- Rabbit anti-APC IHC Antibody, affinity purified
-
预测反应
- Mouse,Rat,Zebrafish,X. tropicalis,Chicken,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Monkey,Gorilla,Chimpanzee,Duckbill platypus,Crab-eating macaque,African elephant,Little brown bat,Zebra finch,Small-eared galago,Gray short-tailed opossum,White-tufted-ear marmoset,Tasmanian devil,Northern white-cheeked gibbon,Naked mole rat
-
纯化方法
- Affinity Purified
-
免疫原
- Between AA 1 and 50
-
亚型
- IgG
-
-
anti-Adenomatous Polyposis Coli (APC) (AA 2636-2845) antibody
APC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (AA 2544-2843) antibodyAPC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (AA 2634-2842) antibodyAPC 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (pSer2054) antibodyAPC 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (C-Term) antibodyAPC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (AA 2744-2843) antibodyAPC 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3E2 unconjugated
anti-Adenomatous Polyposis Coli (APC) (AA 2751-2843) antibodyAPC 适用: 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (C-Term) antibodyAPC 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) antibodyAPC 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) antibodyAPC 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 5F2 unconjugated Recombinant Antibody
-
-
应用备注
- 1:100 - 1:500
-
限制
- 仅限研究用
-
-
-
浓度
- 250 μg/mL
-
缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- APC (Adenomatous Polyposis Coli (APC))
-
别名
- APC
-
背景
- Background: Adenomatosis polyposis coli (APC) is a tumor suppressor gene found to be mutated in most colon cancers and is the cause of familial adenomatous polyposis (FAP), an autosomal dominant disease that results in a predisposition to malignant colon cancer. APC has been shown to be involved in cell differentiation, migration, proliferation and adhesion. One function of APC involves its role as a scaffolding protein that regulates the phosphorylation and degradation of beta-catenin, a transcriptional regulator in the WNT signaling pathway. Additionally, APC has been found to be important in the regulation of microtubule arrays and mitotic spindle formation.
-
基因ID
- 324
-
NCBI登录号
- NP_000029
-
UniProt
- P25054
-
途径
- WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
抗原
-
