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APC 抗体 (AA 1-50)

This anti-APC antibody is a 兔 多克隆 antibody detecting APC in IHC. Suitable for 人.
产品编号 ABIN7448412
发货至: 中国

Quick Overview for APC 抗体 (AA 1-50) (ABIN7448412)

抗原

See all APC 抗体
APC (Adenomatous Polyposis Coli (APC))

适用

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宿主

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克隆类型

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多克隆

标记

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This APC antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-50

    原理

    Rabbit anti-APC IHC Antibody, affinity purified

    预测反应

    Mouse,Rat,Zebrafish,X. tropicalis,Chicken,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Monkey,Gorilla,Chimpanzee,Duckbill platypus,Crab-eating macaque,African elephant,Little brown bat,Zebra finch,Small-eared galago,Gray short-tailed opossum,White-tufted-ear marmoset,Tasmanian devil,Northern white-cheeked gibbon,Naked mole rat

    纯化方法

    Affinity Purified

    免疫原

    Between AA 1 and 50

    亚型

    IgG
  • 应用备注

    1:100 - 1:500

    限制

    仅限研究用
  • 浓度

    250 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    APC (Adenomatous Polyposis Coli (APC))

    别名

    APC

    背景

    Background: Adenomatosis polyposis coli (APC) is a tumor suppressor gene found to be mutated in most colon cancers and is the cause of familial adenomatous polyposis (FAP), an autosomal dominant disease that results in a predisposition to malignant colon cancer. APC has been shown to be involved in cell differentiation, migration, proliferation and adhesion. One function of APC involves its role as a scaffolding protein that regulates the phosphorylation and degradation of beta-catenin, a transcriptional regulator in the WNT signaling pathway. Additionally, APC has been found to be important in the regulation of microtubule arrays and mitotic spindle formation.

    基因ID

    324

    NCBI登录号

    NP_000029

    UniProt

    P25054

    途径

    WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
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