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XBP1 抗体

This anti-XBP1 antibody is a 兔 单克隆 antibody detecting XBP1 in WB. Suitable for 人 和 小鼠.
产品编号 ABIN7384507
发货至: 中国

Quick Overview for XBP1 抗体 (ABIN7384507)

抗原

See all XBP1 抗体
XBP1 (X-Box Binding Protein 1 (XBP1))

适用

  • 72
  • 38
  • 12
  • 6
  • 6
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  • 3
  • 3
  • 2
  • 2
人, 小鼠

宿主

  • 69
  • 14
  • 1

克隆类型

  • 69
  • 15
单克隆

标记

  • 50
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This XBP1 antibody is un-conjugated

应用范围

  • 70
  • 36
  • 25
  • 22
  • 14
  • 13
  • 13
  • 13
  • 10
  • 9
  • 4
  • 3
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  • 1
Western Blotting (WB)

克隆位点

R04-3E2
  • 纯化方法

    Affinity Purified

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000

    限制

    仅限研究用
  • 浓度

    300 μg/mL

    缓冲液

    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    XBP1 (X-Box Binding Protein 1 (XBP1))

    别名

    XBP1

    背景

    Tax responsive element binding protein 5,Tax-responsive element-binding protein 5,TREB5,X box binding protein 1,X box binding protein 2,X-box-binding protein 1,XBP 1,XBP-1,XBP1,XBP1,XBP2,This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor.

    分子量

    Observed_MW: 29kDa

    Calculated_MW: 29kDa

    基因ID

    7494

    UniProt

    P17861

    途径

    ER-Nucleus Signaling, Unfolded Protein Response
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