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ASK1 抗体

MAP3K5 适用: 人 WB 宿主: 兔 Monoclonal R06-4F5 unconjugated
产品编号 ABIN7384417
发货至: 中国
  • 抗原 See all ASK1 (MAP3K5) 抗体
    ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
    适用
    • 167
    • 99
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    • 8
    宿主
    • 175
    • 8
    克隆类型
    • 170
    • 13
    单克隆
    标记
    • 72
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    This ASK1 antibody is un-conjugated
    应用范围
    • 152
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    • 1
    Western Blotting (WB)
    纯化方法
    Affinity Purified
    克隆位点
    R06-4F5
    亚型
    IgG
    Top Product
    Discover our top product MAP3K5 Primary Antibody
  • 应用备注
    WB 1:500-1:1000
    限制
    仅限研究用
  • 浓度
    300 μg/mL
    缓冲液
    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
    别名
    ASK1 (MAP3K5 产品)
    别名
    ASK1 antibody, MAPKKK5 antibody, MEKK5 antibody, mitogen-activated protein kinase kinase kinase 5 antibody, MUD21.11 antibody, MUD21_11 antibody, 7420452D20Rik antibody, ASK antibody, Mekk5 antibody, Ask1 antibody, RGD1306565 antibody, mitogen-activated protein kinase kinase kinase 5 antibody, MAP3K5 antibody, MAPKKK5 antibody, Map3k5 antibody, map3k5 antibody
    背景
    Apoptosis signal regulating kinase 1,Apoptosis signal-regulating kinase 1,ASK 1,ASK-1,ASK1,M3K5,M3K5,MAP/ERK kinase kinase 5,MAP3K5,MAPK/ERK kinase kinase 5,MAPKKK5,MEK kinase 5,MEKK 5,MEKK5,Mitogen activated protein kinase kinase kinase 5,Mitogen-activated protein kinase kinase kinase 5,Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells, MAPKKK5 does not activate MAPK/ERK.
    分子量

    Observed_MW: 155kDa

    Calculated_MW: 155kDa

    基因ID
    4217
    UniProt
    Q99683
    途径
    MAPK Pathway, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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