电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

APC 抗体

This anti-APC antibody is a 兔 单克隆 antibody detecting APC in WB. Suitable for 人.
产品编号 ABIN7384414
发货至: 中国

Quick Overview for APC 抗体 (ABIN7384414)

抗原

See all APC 抗体
APC (Adenomatous Polyposis Coli (APC))

适用

  • 70
  • 42
  • 36
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 94
  • 16
  • 4
  • 2

克隆类型

  • 85
  • 31
单克隆

标记

  • 58
  • 7
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This APC antibody is un-conjugated

应用范围

  • 60
  • 41
  • 30
  • 27
  • 26
  • 26
  • 25
  • 15
  • 12
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)

克隆位点

R06-2E4
  • 纯化方法

    Affinity Purified

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000

    限制

    仅限研究用
  • 浓度

    300 μg/mL

    缓冲液

    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    APC (Adenomatous Polyposis Coli (APC))

    别名

    APC

    背景

    Adenomatous Polyposis Coli,Adenomatous polyposis coli protein,Apc,APC,CC1,Deleted in polyposis 2.5,DP2,DP2.5,DP3,FAP,FPC,GS,Protein APC,This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

    分子量

    Observed_MW: 160kDa

    Calculated_MW: 312kDa

    基因ID

    324

    UniProt

    P25054

    途径

    WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
You are here:
Chat with us!