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Beclin 1 抗体

The 兔 单克隆 anti-Beclin 1 antibody is suitable to detect Beclin 1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN7384332
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Beclin 1 抗体 (ABIN7384332)

抗原

See all Beclin 1 (BECN1) 抗体
Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

适用

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人, 小鼠, 大鼠

宿主

  • 154
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  • 1

克隆类型

  • 141
  • 58
单克隆

标记

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This Beclin 1 antibody is un-conjugated

应用范围

  • 158
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Western Blotting (WB)

克隆位点

R02-8D5
  • 纯化方法

    Affinity Purified

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000

    限制

    仅限研究用
  • 浓度

    300 μg/mL

    缓冲液

    50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

    别名

    Beclin 1

    背景

    APG6,ATG 6,ATG6,ATG6 autophagy related 6 homolog,Bcl-2-interacting protein beclin,Beclin 1 (coiled coil moesin like BCL2 interacting protein),Beclin 1 autophagy related,Beclin-1,Beclin1,BECN 1,Becn1,BECN1,Coiled coil myosin like BCL2 interacting protein,Coiled-coil myosin-like BCL2-interacting protein,GT197,Protein GT197,VPS 30,VPS30,Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.

    分子量

    Observed_MW: 52kDa

    Calculated_MW: 52kDa

    基因ID

    8678

    UniProt

    Q14457

    途径

    Autophagy
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