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RAD50 抗体

This anti-RAD50 antibody is a 兔 多克隆 antibody detecting RAD50 in WB, IHC 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7384000
发货至: 中国

Quick Overview for RAD50 抗体 (ABIN7384000)

抗原

See all RAD50 抗体
RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This RAD50 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 纯化方法

    Affinity purification

    免疫原

    Synthetic peptide of human RAD50

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 浓度

    0.4 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

    别名

    RAD50

    背景

    DNA repair protein RAD50,hRAD50,hsRAD50,Mrell,NBSLD,Rad 50,RAD50 2,rad50,RAD50 homolog (S cerevisiae),RAD50 homolog,RAD50 PEN,RAD50,S. cerevisiae,homolog of,RAD50,RAD502,Rad50l,Truncated RAD50 protein,The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.

    分子量

    154 kDa

    NCBI登录号

    NP_005723

    UniProt

    Q92878

    途径

    DNA Damage Repair, Protein targeting to Nucleus
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