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Vitamin D Receptor 抗体

This anti-Vitamin D Receptor antibody is a 兔 单克隆 antibody detecting Vitamin D Receptor in WB. Suitable for 人.
产品编号 ABIN7271332
发货至: 中国

Quick Overview for Vitamin D Receptor 抗体 (ABIN7271332)

抗原

See all Vitamin D Receptor (VDR) 抗体
Vitamin D Receptor (VDR)

适用

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宿主

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克隆类型

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单克隆

标记

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This Vitamin D Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    VDR Rabbit mAb

    交叉反应

    人, 小鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human VDR.

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Vitamin D Receptor (VDR)

    别名

    VDR

    物质类

    Chemical

    背景

    This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.,VDR,NR1I1,PPP1R163,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,VDR

    分子量

    48kDa/53kDa

    基因ID

    7421

    UniProt

    P11473

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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