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Vitamin D Receptor 抗体 (C-Term)

Name: Vitamin D Receptor 抗体 (C-Term)
SKU: ABIN3043960
Availability: OutOfStock

VDR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Anti-VDR Picoband antibody, Western blotting All lanes: Anti VDR at 0.

Anti-VDR Picoband antibody, IHC(P) IHC(P): Mouse Intestine Tissue

IHC

Anti-VDR Picoband antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue

IHC

Anti-VDR Picoband antibody, IHC(P) IHC(P): Rat Intestine Tissue

IHC

4 images

(2 references)

产品编号 ABIN3043960

发货至: 中国

Datasheet as PDF

抗原 See all Vitamin D Receptor (VDR) 抗体

Vitamin D Receptor (VDR)
抗原表位
15

15

13

10

7

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 377-402, C-Term
适用
90

53

37

2

1

1

1

1

1
人
宿主
97

11

1

1
兔
Compatible Secondaries
克隆类型
91

19
多克隆
标记
55

6

5

5

5

5

5

5

3

3

2

2

2

2

2

2

1
This Vitamin D Receptor antibody is un-conjugated
应用范围
84

32

26

26

15

14

13

10

6

5

4

2

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Vitamin D3 receptor(VDR) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

序列

HLLYAKMIQK LADLRSLNEE HSKQYR

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Vitamin D3 receptor(VDR) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: vitamin D (1,25- dihydroxyvitamin D3) receptor
Protein Name: Vitamin D3 receptor

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human VDR (377-402aa HLLYAKMIQKLADLRSLNEEHSKQYR), different from the related mouse and rat sequences by one amino acid.

亚型

IgG

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VDR 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (AA 1-427) antibody
VDR 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (AA 1-300) antibody
VDR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (N-Term) antibody
VDR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (pSer208) antibody
VDR 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (Ser208) antibody
VDR 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) (AA 266-422) antibody
VDR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vitamin D Receptor (VDR) antibody
VDR 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 3C7 unconjugated Recombinant Antibody

anti-Vitamin D Receptor (VDR) (AA 1-427) antibody
VDR 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F4 unconjugated

anti-Vitamin D Receptor (VDR) (AA 1-428) antibody
VDR 适用: 人 ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F4 unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for VDR is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Hou, Huang, Luo, Wang, Liu, Deng, Zhang, Liu, Chen: "MiR-351 negatively regulates osteoblast differentiation of MSCs induced by (+)-cholesten-3-one through targeting VDR." in: American journal of translational research, Vol. 9, Issue 11, pp. 4963-4973, (2017) (PubMed).

Gao, Wang, Yan, Zeng, Ma, Niu, Zhou, Jiang, Chen: "Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats." in: PLoS ONE, Vol. 11, Issue 3, pp. e0151118, (2016) (PubMed).
抗原

Vitamin D Receptor (VDR)

别名

VDR (VDR 产品)

别名

vdrbeta antibody, vdr0 antibody, LOC100136219 antibody, NR1I1-B antibody, gb:dq017633 antibody, vdr-b antibody, Ci-VDR-b antibody, VDR antibody, LOC100221284 antibody, vdr-A antibody, xVDR antibody, Nr1i1 antibody, vdr antibody, NR1I1 antibody, PPP1R163 antibody, vitamin D (1,25- dihydroxyvitamin D3) receptor antibody, vitamin D receptor antibody, vitamin D3 receptor A antibody, vitamin D receptor b antibody, nuclear receptor VDR-b antibody, vitamin D (1,25- dihydroxyvitamin D3) receptor L homeolog antibody, vitamin D (1,25-dihydroxyvitamin D3) receptor antibody, vitamin D receptor a antibody, vdr antibody, vdr0 antibody, VDR antibody, LOC100136219 antibody, vdrb antibody, vdr-b antibody, vdr.L antibody, Vdr antibody, vdra antibody

物质类

Chemical

背景

VDR (Vitamin D Receptor), also known as Vitamin D Hormone Receptor, is a member of the nuclear receptor family of transcription factors. Labuda et al. (1991) assigned the VDR gene to 12q12-q14 by in situ hybridization. Using mutation analysis, Jurutka et al. (2000) characterized arg18/arg22, VDR residues immediately N-terminal of the first DNA-binding zinc finger, as vital for contact with the general transcription factor IIB (TFIIB). A natural polymorphic variant of VDR, termed F/M4 (missing a FokI restriction site), which lacks only the first 3 amino acids (including glu2), interacted more efficiently with TFIIB and also possessed elevated transcriptional activity compared with the full-length (f/M1) receptor. Shah et al. (2006) stated that the signaling and oncogenic activity of beta-catenin (CTNNB1) can be repressed by activation of VDR. Conversely, high levels of beta-catenin can potentiate the transcriptional activity of 1,25- dihydroxyvitamin D3.

Synonyms: 1 25 dihydroxyvitamin D3 receptor antibody|1 antibody|1,25-@dihydroxyvitamin D3 receptor antibody|125 dihydroxyvitamin D3 receptor antibody|25-dihydroxyvitamin D3 receptor antibody|Member 1 antibody|NR1I1 antibody|Nuclear receptor subfamily 1 group I member 1 antibody|VDR antibody|VDR_HUMAN antibody|Vitamin D (1,25- dihydroxyvitamin D3) receptor antibody|Vitamin D hormone receptor antibody|Vitamin D nuclear receptor variant 1 antibody| Vitamin D receptor antibody|Vitamin D3 receptor antibody

基因ID

7421

UniProt

P11473

途径

Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway