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TRIM5 抗体 (AA 100-200)

This anti-TRIM5 antibody is a 兔 多克隆 antibody detecting TRIM5 in WB. Suitable for 人.
产品编号 ABIN7270992
发货至: 中国

Quick Overview for TRIM5 抗体 (AA 100-200) (ABIN7270992)

抗原

See all TRIM5 抗体
TRIM5 (Tripartite Motif Containing 5 (TRIM5))

适用

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宿主

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克隆类型

  • 35
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多克隆

标记

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This TRIM5 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 100-200

    原理

    TRIM5 Rabbit pAb

    序列

    EKLLLFCQED GKVICWLCER SQEHRGHHTF LTEEVAREYQ VKLQAALEML RQKQQEAEEL EADIREEKAS WKTQIQYDKT NVLADFEQLR DILDWEESNE L

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TRIM5 (NP_149083.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TRIM5 (Tripartite Motif Containing 5 (TRIM5))

    别名

    TRIM5

    背景

    The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.,TRIM5,RNF88,TRIM5alpha,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,Immunology & Inflammation,TRIM5

    分子量

    29kDa/31kDa/37kDa/40kDa/46kDa/56kDa

    基因ID

    85363

    UniProt

    Q9C035

    途径

    Activation of Innate immune Response
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