TRIM5 抗体 (AA 100-200)
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北京 101111
Quick Overview for TRIM5 抗体 (AA 100-200) (ABIN7270992)
抗原
See all TRIM5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-200
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原理
- TRIM5 Rabbit pAb
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序列
- EKLLLFCQED GKVICWLCER SQEHRGHHTF LTEEVAREYQ VKLQAALEML RQKQQEAEEL EADIREEKAS WKTQIQYDKT NVLADFEQLR DILDWEESNE L
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TRIM5 (NP_149083.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TRIM5 (Tripartite Motif Containing 5 (TRIM5))
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别名
- TRIM5
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背景
- The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.,TRIM5,RNF88,TRIM5alpha,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,Immunology & Inflammation,TRIM5
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分子量
- 29kDa/31kDa/37kDa/40kDa/46kDa/56kDa
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基因ID
- 85363
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UniProt
- Q9C035
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途径
- Activation of Innate immune Response
抗原
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