TXNRD1 抗体
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北京 101111
Quick Overview for TXNRD1 抗体 (ABIN7270805)
抗原
See all TXNRD1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Thioredoxin reductase 1 (TXNRD1 ) Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human Thioredoxin reductase 1 (Thioredoxin reductase 1 (TXNRD1 ) )
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
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别名
- TXNRD1
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背景
- This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq, Jul 2008],GRIM-12, TR, TR1, TRXR1, TXNR,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Signal Transduction,TXNRD1
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分子量
- 55kDa
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基因ID
- 7296
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UniProt
- Q16881
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途径
- Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
抗原
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