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RAD50 抗体

This anti-RAD50 antibody is a 兔 单克隆 antibody detecting RAD50 in WB. Suitable for 人.
产品编号 ABIN7269826
发货至: 中国

Quick Overview for RAD50 抗体 (ABIN7269826)

抗原

See all RAD50 抗体
RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

适用

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宿主

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克隆类型

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单克隆

标记

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This RAD50 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    Rad50 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human Rad50

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

    别名

    RAD50

    背景

    The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010],NBSLD, RAD502, hRad50,Cell Biology & Developmental Biology,Cell Cycle,DNA Damage & Repair,Epigenetics & Nuclear Signaling,G2/M DNA Damage Checkpoint,RAD50

    分子量

    154kDa

    基因ID

    10111

    UniProt

    Q92878

    途径

    DNA Damage Repair, Protein targeting to Nucleus
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