PPP3CA 抗体
Quick Overview for PPP3CA 抗体 (ABIN7269692)
抗原
See all PPP3CA 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Calcineurin A Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human Calcineurin A
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亚型
- IgG
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anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (AA 1-84) antibody
PPP3CA 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2G8 unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (AA 1-511) antibodyPPP3CA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (Middle Region) antibodyPPP3CA 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (AA 21-51) antibodyPPP3CA 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) antibodyPPP3CA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) antibodyPPP3CA 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CALNA-2353 unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (N-Term) antibodyPPP3CA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (N-Term) antibodyPPP3CA 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) antibodyPPP3CA 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (AA 364-283) antibodyPPP3CA 适用: 人, 小鼠, 大鼠, 犬, 兔 WB, IHC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PPP3CA (Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))
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别名
- PPP3CA
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背景
- Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+-mediated signals. Many of the substrates contain a PxIxIT motif and/or a LxVP motif. In response to increased Ca(2+ levels, dephosphorylates and activates phosphatase SSH1 which results in cofilin dephosphorylation. In response to increased Ca(2+ levels following mitochondrial depolarization, dephosphorylates DNM1L inducing DNM1L translocation to the mitochondrion. Dephosphorylates heat shock protein HSPB1 (By similarity. Dephosphorylates and activates transcription factor NFATC1. In response to increased Ca(2+ levels, regulates NFAT-mediated transcription probably by dephosphorylating NFAT and promoting its nuclear translocation. Dephosphorylates and inactivates transcription factor ELK1. Dephosphorylates DARPP32. May dephosphorylate CRTC2 at 'Ser-171' resulting in CRTC2 dissociation from 14-3-3 proteins. Dephosphorylates transcription factor TFEB at 'Ser-211' following Coxsackievirus B3 infection, promoting nuclear translocation.,CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B,B Cell Receptor Signaling Pathway,Calcium Signaling,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Actins,ErbB-HER Signaling Pathway,Immunology & Inflammation,Neurodegenerative Diseases,Neuroscience,Signal Transduction,T Cell Receptor Signaling Pathway,PPP3CA
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分子量
- 59kDa
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基因ID
- 5530
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UniProt
- Q08209
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途径
- RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Synaptic Membrane, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling
抗原
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