Quick Overview for PKM1 抗体 (ABIN7269382)
抗原
PKM1
适用
人
宿主
兔
克隆类型
单克隆
标记
非结合性
应用范围
Western Blotting (WB)
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原理
- PKM1-specific Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of Human PKM1.
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亚型
- IgG
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anti-PKM1 (AA 383-417), (C-Term) antibody
适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB18404 unconjugated
anti-PKM1 antibody适用: 人 WB 宿主: 小鼠 Monoclonal OTI3C6 unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PKM1
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背景
- This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011],CTHBP,HEL-S-30,OIP3,PK3,PKM2,TCB,THBP1,PKM,Cancer,Carbohydrate metabolism,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Protein phosphorylation,RNA Binding,Signal Transduction,Tumor biomarkers,Warburg Effect,PKM1
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分子量
- 58kDa
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基因ID
- 5315
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UniProt
- P14618
抗原
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