MAP3K3 抗体 (AA 1-220)
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北京 101111
Quick Overview for MAP3K3 抗体 (AA 1-220) (ABIN7268652)
抗原
See all MAP3K3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-220
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原理
- MEKK3 Rabbit pAb
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序列
- MDEQEALNSI MNDLVALQMN RRHRMPGYET MKNKDTGHSN RQKKHNSSSS ALLNSPTVTT SSCAGASEKK KFLSDVRIKF EHNGERRIIA FSRPVKYEDV EHKVTTVFGQ PLDLHYMNNE LSILLKNQDD LDKAIDILDR SSSMKSLRIL LLSQDRNHNS SSPHSGVSRQ VRIKASQSAG DINTIYQPPE PRSRHLSVSS QNPGRSSPPP GYVPERQQHI
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human MEKK3 (NP_976226.1).
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) antibody
MAP3K3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (AA 11-25), (N-Term) antibodyMAP3K3 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (N-Term) antibodyMAP3K3 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (AA 1-90) antibodyMAP3K3 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (Center) antibodyMAP3K3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (Internal Region) antibodyMAP3K3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) antibodyMAP3K3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2870 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) antibodyMAP3K3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (Internal Region) antibodyMAP3K3 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (AA 1-89) antibodyMAP3K3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H3 unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))
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别名
- MAP3K3
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背景
- This gene product is a 626-amino acid polypeptide that is 96.5 % identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively, it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed.,MAP3K3,MAPKKK3,MEKK3,Signal Transduction,Kinase,Serine/threonine kinases,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,MAP3K3
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分子量
- 70kDa/74kDa
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基因ID
- 4215
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UniProt
- Q99759
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途径
- MAPK Pathway
抗原
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