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MEK2 抗体 (AA 1-100)

Name: MEK2 抗体 (AA 1-100)
Brand: antibodies-online
SKU: ABIN7268640
Availability: OutOfStock

This 兔多克隆 anti-MEK2 antibody specifically detects MEK2 in WB, IHC 和 IF. The antibody is reactive with 人 samples.

Western blot analysis of extracts of HeLa cells, using MEK2 antibody (ABIN7268640) at 1:1000 dilution. (MEK2 抗体 (AA 1-100))

Immunofluorescence analysis of U2OS cells using MEK2 antibody (ABIN7268640) at dilution of 1:100. (MEK2 抗体 (AA 1-100))

Western blot analysis of extracts of various cell lines, using MEK2 antibody (ABIN7268640) at 1:1000 dilution. (MEK2 抗体 (AA 1-100))

Immunofluorescence analysis of NIH/3T3 cells using MEK2 antibody (ABIN7268640) at dilution of 1:100. (MEK2 抗体 (AA 1-100))

4 images

产品编号 ABIN7268640

发货至: 中国

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中国
北京 101111

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Quick Overview for MEK2 抗体 (AA 1-100) (ABIN7268640)

抗原

See all MEK2 (MAP2K2) 抗体

MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

适用

人

宿主

兔

克隆类型

多克隆

标记

This MEK2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

质量等级

KO Validated

Discover our top product MAP2K2 Primary Antibody

抗原表位
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AA 1-100

原理

[KO Validated] MEK2 Rabbit pAb

序列

MLARRKPVLP ALTINPTIAE GPSPTSEGAS EANLVDLQKK LEELELDEQQ KKRLEAFLTQ KAKVGELKDD DFERISELGA GNGGVVTKVQ HRPSGLIMAR

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MEK2 (NP_109587.1).

亚型

IgG
anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-50) antibody
MAP2K2 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 44-313) antibody
MAP2K2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-30), (N-Term) antibody
MAP2K2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal RB3595 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-400) antibody
MAP2K2 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-360) antibody
MAP2K2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 8D10 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 200-229) antibody
MAP2K2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB12322 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 262-292) antibody
MAP2K2 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB3597 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 264-400) antibody
MAP2K2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (pThr394) antibody
MAP2K2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 372-400) antibody
MAP2K2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB14015 unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
抗原

MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

别名

MAP2K2

背景

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.,CFC4,MAPKK2,MEK2,MKK2,PRKMK2,MAP2K2,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,Tyrosine kinases,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Warburg Effect,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Angiogenesis,MAP2K2

分子量

44kDa

基因ID

5605

UniProt

P36507

途径

MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling