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MICA 抗体

MICA 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7268508
发货至: 中国
  • 抗原 See all MICA 抗体
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    适用
    • 69
    • 18
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    • 7
    • 5
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    • 1
    宿主
    • 36
    • 33
    克隆类型
    • 37
    • 33
    单克隆
    标记
    • 44
    • 8
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MICA antibody is un-conjugated
    应用范围
    • 44
    • 37
    • 33
    • 19
    • 17
    • 12
    • 9
    • 8
    • 6
    • 5
    • 5
    • 4
    • 2
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    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    MICA Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human MICA.
    亚型
    IgG
    Top Product
    Discover our top product MICA Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    别名
    MICA (MICA 产品)
    别名
    MIC-A antibody, PERB11.1 antibody, MHC class I polypeptide-related sequence A antibody, MICA antibody
    背景
    This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.,MICA, MIC-A, PERB11.1, MHC class I polypeptide-related sequence A,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,MICA
    分子量
    42-70kDa
    基因ID
    100507436
    UniProt
    Q29983
    途径
    Activation of Innate immune Response, Transition Metal Ion Homeostasis
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