电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

MBD2 抗体

This 兔 单克隆 anti-MBD2 antibody specifically detects MBD2 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN7268491
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MBD2 抗体 (ABIN7268491)

抗原

See all MBD2 抗体
MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

适用

  • 66
  • 34
  • 17
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 63
  • 2
  • 1

克隆类型

  • 42
  • 24
单克隆

标记

  • 31
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This MBD2 antibody is un-conjugated

应用范围

  • 58
  • 26
  • 23
  • 22
  • 18
  • 15
  • 12
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 原理

    MBD2 Rabbit mAb

    交叉反应

    小鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human MBD2

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

    别名

    MBD2

    背景

    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011],DMTase, NY-CO-41,Epigenetics & Nuclear Signaling,MBD2

    分子量

    29,43kDa

    基因ID

    8932

    UniProt

    Q9UBB5

    途径

    Chromatin Binding
You are here: