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MASP2 抗体 (AA 445-686)

This anti-MASP2 antibody (ABIN7268387) is a Rabbit Polyclonal antibody detecting MASP2 in WB. Suitable for Human.
产品编号 ABIN7268387
发货至: 中国

Quick Overview for MASP2 抗体 (AA 445-686) (ABIN7268387)

抗原

See all MASP2 抗体
MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

适用

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宿主

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克隆类型

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多克隆

标记

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This MASP2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 445-686

    原理

    MASP2 Rabbit pAb

    序列

    IYGGQKAKPG DFPWQVLILG GTTAAGALLY DNWVLTAAHA VYEQKHDASA LDIRMGTLKR LSPHYTQAWS EAVFIHEGYT HDAGFDNDIA LIKLNNKVVI NSNITPICLP RKEAESFMRT DDIGTASGWG LTQRGFLARN LMYVDIPIVD HQKCTAAYEK PPYPRGSVTA NMLCAGLESG GKDSCRGDSG GALVFLDSET ERWFVGGIVS WGSMNCGEAG QYGVYTKVIN YIPWIENIIS DF

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 445-686 of human MASP2 (NP_006601.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

    别名

    MASP2

    背景

    This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,MASP2,MAP19,MASP-2,MASP1P1,sMAP,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Blood,Serum Proteins,MASP2

    分子量

    20kDa/75kDa

    基因ID

    10747

    UniProt

    O00187

    途径

    Complement System
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