ITCH 抗体 (AA 50-150)
Quick Overview for ITCH 抗体 (AA 50-150) (ABIN7268033)
抗原
See all ITCH 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 50-150
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原理
- [KO Validated] ITCH Rabbit pAb
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序列
- QSKKTEKCNN TNSPKWKQPL TVIVTPVSKL HFRVWSHQTL KSDVLLGTAA LDIYETLKSN NMKLEEVVVT LQLGGDKEPT ETIGDLSICL DGLQLESEVV T
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ITCH (NP_001244066.1).
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亚型
- IgG
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anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (Internal Region) antibody
Verified ITCH 适用: 人 ELISA, WB, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) antibodyKO Validated ITCH 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (Tyr420) antibodyITCH 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (AA 29-303) antibodyITCH 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (AA 92-190) antibodyITCH 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) antibodyITCH 适用: 人 ELISA, WB 宿主: 兔 Monoclonal 9C3 unconjugated Recombinant Antibody
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (pTyr420) antibodyITCH 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (AA 143-192) antibodyITCH 适用: 人, Cow, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (AA 410-437), (Middle Region) antibodyITCH 适用: 人, 小鼠, 大鼠, 猴 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
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别名
- ITCH
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背景
- This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,ITCH,ADMFD,AIF4,AIP4,NAPP1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Notch Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,ITCH
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分子量
- 103kDa
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基因ID
- 83737
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UniProt
- Q96J02
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途径
- Activation of Innate immune Response, CXCR4-mediated Signaling Events
抗原
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