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Insulin Receptor 抗体 (AA 1281-1382)

INSR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7267890
发货至: 中国
  • 抗原 See all Insulin Receptor (INSR) 抗体
    Insulin Receptor (INSR)
    抗原表位
    • 16
    • 15
    • 13
    • 12
    • 8
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    AA 1281-1382
    适用
    • 165
    • 96
    • 81
    • 16
    • 13
    • 9
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
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    宿主
    • 162
    • 23
    • 3
    • 1
    克隆类型
    • 155
    • 34
    多克隆
    标记
    • 114
    • 16
    • 16
    • 7
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    • 3
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    This Insulin Receptor antibody is un-conjugated
    应用范围
    • 139
    • 81
    • 52
    • 27
    • 16
    • 15
    • 14
    • 14
    • 13
    • 13
    • 7
    • 5
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    • 1
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    Western Blotting (WB), Immunoprecipitation (IP)
    原理
    Insulin Receptor Rabbit pAb
    序列
    PTFLEIVNLL KDDLHPSFPE VSFFHSEENK APESEELEME FEDMENVPLD RSSHCQREEA GGRDGGSSLG FKRSYEEHIP YTHMNGGKKN GRILTLPRSN PS
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1281-1382 of human INSR (NP_000199.2).
    亚型
    IgG
    Top Product
    Discover our top product INSR Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IP,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Insulin Receptor (INSR)
    别名
    INSR (INSR 产品)
    别名
    CD220 antibody, HHF5 antibody, 4932439J01Rik antibody, D630014A15Rik antibody, IR antibody, IR-A antibody, IR-B antibody, 18402 antibody, CG18402 antibody, DIHR antibody, DILR antibody, DIR antibody, DIRH antibody, DIRbeta antibody, DInR antibody, DInr antibody, Dir-a antibody, Dir-b antibody, Dmel\\CG18402 antibody, INR antibody, INS antibody, Inr antibody, Inr-alpha antibody, Inr-beta antibody, InsR antibody, dINR antibody, dIR antibody, dIRH antibody, dInR antibody, dInr antibody, dInsR antibody, dinr antibody, dir antibody, er10 antibody, inr antibody, insulin/insulin-like growth factor receptor antibody, l(3)05545 antibody, l(3)93Dj antibody, l(3)er10 antibody, lnR antibody, ir-A antibody, CTK-1 antibody, ir antibody, INSR antibody, NV14476 antibody, cd220 antibody, hhf5 antibody, insulin receptor antibody, Insulin-like receptor antibody, insulin receptor L homeolog antibody, INSR antibody, Insr antibody, InR antibody, LOC100122567 antibody, LOC100451802 antibody, insr.L antibody
    背景
    This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.,CD220,HHF5,INSR,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Insulin and insulin-like,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Immunology & Inflammation,CD markers,Neuroscience,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,INSR
    分子量
    155kDa/156kDa
    基因ID
    3643
    UniProt
    P06213
    途径
    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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