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HSPA2 抗体

This anti-HSPA2 antibody is a 兔 单克隆 antibody detecting HSPA2 in WB 和 IF. Suitable for 人.
产品编号 ABIN7267579
发货至: 中国

Quick Overview for HSPA2 抗体 (ABIN7267579)

抗原

See all HSPA2 抗体
HSPA2 (Heat Shock 70kDa Protein 2 (HSPA2))

适用

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宿主

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克隆类型

  • 40
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单克隆

标记

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This HSPA2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 原理

    HSPA2 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human HSPA2

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    HSPA2 (Heat Shock 70kDa Protein 2 (HSPA2))

    别名

    HSPA2

    背景

    Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release. Plays a role in spermatogenesis. In association with SHCBP1L may participate in the maintenance of spindle integrity during meiosis in male germ cells (By similarity.,HSP70-2, HSP70-3,Cancer,Endocrine & Metabolism,Mitochondrial metabolism,Signal Transduction,Tumor biomarkers,HSPA2

    分子量

    70kDa

    基因ID

    3306

    UniProt

    P54652
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