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HSPA2 抗体 (AA 400-639)

HSPA2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6142040
发货至: 中国
  • 抗原 See all HSPA2 抗体
    HSPA2 (Heat Shock 70kDa Protein 2 (HSPA2))
    抗原表位
    • 8
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 400-639
    适用
    • 48
    • 25
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 39
    • 17
    克隆类型
    • 31
    • 25
    多克隆
    标记
    • 30
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This HSPA2 antibody is un-conjugated
    应用范围
    • 41
    • 15
    • 12
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    TPLSLGIETA GGVMTPLIKR NTTIPTKQTQ TFTTYSDNQS SVLVQVYEGE RAMTKDNNLL GKFDLTGIPP APRGVPQIEV TFDIDANGIL NVTAADKSTG KENKITITND KGRLSKDDID RMVQEAERYK SEDEANRDRV AAKNALESYT YNIKQTVEDE KLRGKISEQD KNKILDKCQE VINWLDRNQM AEKDEYEHKQ KELERVCNPI ISKLYQGGPG GGSGGGGSGA SGGPTIEEVD
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 400-639 of human HSPA2 (NP_068814.2).
    亚型
    IgG
    Top Product
    Discover our top product HSPA2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    HSPA2 (Heat Shock 70kDa Protein 2 (HSPA2))
    别名
    HSPA2 (HSPA2 产品)
    别名
    HSP70-2 antibody, HSP70-3 antibody, HSPA2 antibody, DKFZp468B217 antibody, 70kDa antibody, HSP70.2 antibody, HSP70A2 antibody, Hsp70-2 antibody, Hspt70 antibody, Hst70 antibody, HSPA3 antibody, heat shock protein family A (Hsp70) member 2 antibody, heat shock protein Hsp20 antibody, heat shock 70kDa protein 2 antibody, heat shock protein 2 antibody, heat shock protein family A member 2 antibody, HSPA2 antibody, hspA2 antibody, Hspa2 antibody
    背景
    Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release. Plays a role in spermatogenesis. In association with SHCBP1L may participate in the maintenance of spindle integrity during meiosis in male germ cells (By similarity.,HSPA2,HSP70-2,HSP70-3,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,HSPA2
    分子量
    70 kDa
    基因ID
    3306
    UniProt
    P54652
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