Growth Hormone Receptor 抗体 (AA 26-260)
Quick Overview for Growth Hormone Receptor 抗体 (AA 26-260) (ABIN7267519)
抗原
See all Growth Hormone Receptor (GHR) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 26-260
-
原理
- GHR Rabbit pAb
-
序列
- FSGSEATAAI LSRAPWSLQS VNPGLKTNSS KEPKFTKCRS PERETFSCHW TDEVHHGTKN LGPIQLFYTR RNTQEWTQEW KECPDYVSAG ENSCYFNSSF TSIWIPYCIK LTSNGGTVDE KCFSVDEIVQ PDPPIALNWT LLNVSLTGIH ADIQVRWEAP RNADIQKGWM VLEYELQYKE VNETKWKMMD PILTTSVPVY SLKVDKEYEV RVRSKQRNSG NYGEFSEVLY VTLPQ
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 26-260 of human GHR (NP_001229328.1).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Growth Hormone Receptor (GHR)
-
别名
- GHR
-
背景
- This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.,GHR,GHBP,GHIP,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Growth factor,GHR
-
分子量
- 33kDa/34kDa/69kDa/71kDa
-
基因ID
- 2690
-
UniProt
- P10912
-
途径
- NF-kappaB Signaling, JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
-