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Growth Hormone Receptor 抗体 (AA 26-260)

This anti-Growth Hormone Receptor antibody is a 兔 多克隆 antibody detecting Growth Hormone Receptor in WB. Suitable for 人.
产品编号 ABIN7267519
发货至: 中国

Quick Overview for Growth Hormone Receptor 抗体 (AA 26-260) (ABIN7267519)

抗原

See all Growth Hormone Receptor (GHR) 抗体
Growth Hormone Receptor (GHR)

适用

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宿主

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克隆类型

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多克隆

标记

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This Growth Hormone Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 26-260

    原理

    GHR Rabbit pAb

    序列

    FSGSEATAAI LSRAPWSLQS VNPGLKTNSS KEPKFTKCRS PERETFSCHW TDEVHHGTKN LGPIQLFYTR RNTQEWTQEW KECPDYVSAG ENSCYFNSSF TSIWIPYCIK LTSNGGTVDE KCFSVDEIVQ PDPPIALNWT LLNVSLTGIH ADIQVRWEAP RNADIQKGWM VLEYELQYKE VNETKWKMMD PILTTSVPVY SLKVDKEYEV RVRSKQRNSG NYGEFSEVLY VTLPQ

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 26-260 of human GHR (NP_001229328.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Growth Hormone Receptor (GHR)

    别名

    GHR

    背景

    This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.,GHR,GHBP,GHIP,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Growth factor,GHR

    分子量

    33kDa/34kDa/69kDa/71kDa

    基因ID

    2690

    UniProt

    P10912

    途径

    NF-kappaB Signaling, JAK/STAT Signaling, Response to Growth Hormone Stimulus
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