GDNF 抗体 (AA 109-211)
Quick Overview for GDNF 抗体 (AA 109-211) (ABIN7267388)
抗原
See all GDNF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 109-211
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原理
- GDNF Rabbit pAb
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序列
- RGQRGKNRGC VLTAIHLNVT DLGLGYETKE ELIFRYCSGS CDAAETTYDK ILKNLSRNRR LVSDKVGQAC CRPIAFDDDL SFLDDNLVYH ILRKHSAKRC GCI
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交叉反应
- 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 109-211 of human GDNF (NP_000505.1).
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亚型
- IgG
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anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 121-211) antibody
GDNF 适用: 人, 小鼠, 大鼠, Cow, 兔 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) antibodyGDNF 适用: 人 WB, IHC, ELISA, IP, FACS 宿主: 兔 Monoclonal 11D2 unconjugated Recombinant Antibody
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 142-158), (Middle Region) antibodyGDNF 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 8-36) antibodyGDNF 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 192-207), (Mature) antibodyGDNF 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 121-211) antibody (FITC)GDNF 适用: 人, 小鼠, 大鼠, Cow, 兔 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal FITC
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 78-211) antibodyGDNF 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 78-211) antibodyGDNF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 79-217) antibodyGDNF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) antibodyGDNF 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
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别名
- GDNF
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背景
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing.,GDNF,ATF,ATF1,ATF2,HFB1-GDNF,HSCR3,Cell Biology & Developmental Biology,Apoptosis,Growth factor,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Other Neurological disorders,Amyotrophic lateral sclerosis-ALS,GDNF
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分子量
- 18kDa/20kDa/22kDa/23kDa/25kDa
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基因ID
- 2668
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UniProt
- P39905
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途径
- RTK signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
抗原
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