GLI3 抗体 (AA 800-900)
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北京 101111
Quick Overview for GLI3 抗体 (AA 800-900) (ABIN7267386)
抗原
See all GLI3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 800-900
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原理
- GLI3 Rabbit pAb
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序列
- KAPAVSPLIG NGTQSNNTCS LGGPMTLLPG RSDLSGVDVT MLNMLNRRDS SASTISSAYL SSRRSSGISP CFSSRRSSEA SQAEGRPQNV SVADSYDPIS T
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 800-900 of human GLI3 (NP_000159.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GLI3 (GLI Family Zinc Finger 3 (GLI3))
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别名
- GLI3
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背景
- This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.,GLI3,ACLS,GCPS,GLI3-190,GLI3FL,PAP-A,PAPA,PAPA1,PAPB,PHS,PPDIV,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Neuroscience,Stem Cells,GLI3
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分子量
- 169kDa
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基因ID
- 2737
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UniProt
- P10071
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途径
- Hedgehog Signaling
抗原
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