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FANCD2 抗体

This anti-FANCD2 antibody is a 兔 单克隆 antibody detecting FANCD2 in WB. Suitable for 人.
产品编号 ABIN7267126
发货至: 中国

Quick Overview for FANCD2 抗体 (ABIN7267126)

抗原

See all FANCD2 抗体
FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

适用

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宿主

  • 70
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克隆类型

  • 61
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单克隆

标记

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This FANCD2 antibody is un-conjugated

应用范围

  • 27
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Western Blotting (WB)
  • 原理

    FANCD2 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human FANCD2.

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

    别名

    FANCD2

    背景

    The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],FA4,FAD,FACD,FAD2,FA-D2,FANCD,FANCD2,Cell Biology & Developmental Biology,Cell Cycle,DNA Damage & Repair,Epigenetics & Nuclear Signaling,G2/M DNA Damage Checkpoint,FANCD2

    分子量

    166kDa

    基因ID

    2177

    UniProt

    Q9BXW9

    途径

    DNA Damage Repair
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