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PERK 抗体 (pThr982)

EIF2AK3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7267032
发货至: 中国
  • 抗原 See all PERK (EIF2AK3) 抗体
    PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
    抗原表位
    • 16
    • 16
    • 11
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr982
    适用
    • 118
    • 75
    • 73
    • 16
    • 16
    宿主
    • 110
    • 5
    • 3
    • 1
    克隆类型
    • 114
    • 5
    多克隆
    标记
    • 42
    • 12
    • 9
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    This PERK antibody is un-conjugated
    应用范围
    • 79
    • 58
    • 45
    • 28
    • 26
    • 26
    • 14
    • 10
    • 8
    • 6
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB)
    原理
    Phospho-PERK-T982 Rabbit pAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Phosphorylated Antibodies
    纯化方法
    Affinity purification
    免疫原
    A phospho specific peptide corresponding to residues surrounding T982 of human PERK.
    亚型
    IgG
    Top Product
    Discover our top product EIF2AK3 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
    别名
    EIF2AK3 (EIF2AK3 产品)
    别名
    EIF2AK3 antibody, AI427929 antibody, Pek antibody, Perk antibody, PEK antibody, PERK antibody, WRS antibody, eukaryotic translation initiation factor 2 alpha kinase 3 antibody, EIF2AK3 antibody, Eif2ak3 antibody
    背景
    The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.,EIF2AK3,PEK,PERK,WRS,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF2,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Protein folding,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Neuroscience,Neurodegenerative Diseases,Protein phosphorylation,EIF2AK3
    分子量
    125kDa
    基因ID
    9451
    UniProt
    Q9NZJ5
    途径
    Hormone Transport, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response
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