EGFR 抗体 (pTyr1173)
Quick Overview for EGFR 抗体 (pTyr1173) (ABIN7266990)
抗原
See all EGFR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr1173
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原理
- Phospho-EGFR-Y1173 Rabbit pAb
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交叉反应
- 人
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产品特性
- Phosphorylated Antibodies
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纯化方法
- Affinity purification
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免疫原
- A phospho specific peptide corresponding to residues surrounding Y1173 of human EGFR
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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别名
- EGFR
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背景
- The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016],ERBB, ERBB1, HER1, NISBD2, PIG61, mENA,Angiogenesis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,ErbB-HER Signaling Pathway,G protein signaling,Growth factors,Growth factors_EGF,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Kinase,Kinase_Tyrosine kinases,Phospholipase Signaling Pathway,Protein phosphorylation,Signal Transduction,Tumor biomarkers,EGFR
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分子量
- 175kDa
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基因ID
- 1956
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UniProt
- P00533
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途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
抗原
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