Calpain S1 抗体
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北京 101111
Quick Overview for Calpain S1 抗体 (ABIN7266036)
抗原
See all Calpain S1 (CAPNS1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Calpain small subunit 1 Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human Calpain small subunit 1
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))
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别名
- CAPNS1
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背景
- This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014],CALPAIN4, CANP, CANPS, CAPN4, CDPS, CSS1,Calcium Signaling,Immunology & Inflammation,Neuroscience,Signal Transduction,T Cell Receptor Signaling Pathway,CAPNS1
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分子量
- 28kDa
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基因ID
- 826
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UniProt
- P04632
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途径
- Apoptosis
抗原
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