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Axin 抗体 (AA 1-351)

This anti-Axin antibody is a 兔 多克隆 antibody detecting Axin in WB. Suitable for 人.
产品编号 ABIN7265799
发货至: 中国

Quick Overview for Axin 抗体 (AA 1-351) (ABIN7265799)

抗原

See all Axin (AXIN1) 抗体
Axin (AXIN1) (Axin 1 (AXIN1))

适用

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宿主

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克隆类型

  • 94
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多克隆

标记

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This Axin antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-351

    原理

    AXIN1 Rabbit pAb

    序列

    MNIQEQGFPL DLGASFTEDA PRPPVPGEEG ELVSTDPRPA SYSFCSGKGV GIKGETSTAT PRRSDLDLGY EPEGSASPTP PYLKWAESLH SLLDDQDGIS LFRTFLKQEG CADLLDFWFA CTGFRKLEPC DSNEEKRLKL ARAIYRKYIL DNNGIVSRQT KPATKSFIKG CIMKQLIDPA MFDQAQTEIQ ATMEENTYPS FLKSDIYLEY TRTGSESPKV CSDQSSGSGT GKGISGYLPT LNEDEEWKCD QDMDEDDGRD AAPPGRLPQK LLLETAAPRV SSSRRYSEGR EFRYGSWREP VNPYYVNAGY ALAPATSAND SEQQSLSSDA DTLSLTDSSV DGIPPYRIRK Q

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human AXIN1 (NP_851393.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Axin (AXIN1) (Axin 1 (AXIN1))

    别名

    AXIN1

    背景

    This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants.,AXIN1,AXIN,PPP1R49,axin-1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Stem Cells,AXIN1

    分子量

    91kDa/95kDa

    基因ID

    8312

    UniProt

    O15169

    途径

    WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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