alpha 2 Macroglobulin 抗体 (AA 1155-1474)
Quick Overview for alpha 2 Macroglobulin 抗体 (AA 1155-1474) (ABIN7265559)
抗原
See all alpha 2 Macroglobulin (A2M) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1155-1474
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原理
- Alpha-2-Macroglobulin (A2M) Rabbit pAb
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序列
- ALAGNQDKRK EVLKSLNEEA VKKDNSVHWE RPQKPKAPVG HFYEPQAPSA EVEMTSYVLL AYLTAQPAPT SEDLTSATNI VKWITKQQNA QGGFSSTQDT VVALHALSKY GAATFTRTGK AAQVTIQSSG TFSSKFQVDN NNRLLLQQVS LPELPGEYSM KVTGEGCVYL QTSLKYNILP EKEEFPFALG VQTLPQTCDE PKAHTSFQIS LSVSYTGSRS ASNMAIVDVK MVSGFIPLKP TVKMLERSNH VSRTEVSSNH VLIYLDKVSN QTLSLFFTVL QDVPVRDLKP AIVKVYDYYE TDEFAIAEYN APCSKDLGNA
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1155-1474 of human Alpha-2-Macroglobulin (Alpha-2-Macroglobulin (A2M)) (NP_000005.2).
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亚型
- IgG
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anti-alpha-2-Macroglobulin (A2M) (AA 616-856) antibody
A2M 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) antibodyA2M 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 616-856) antibodyA2M 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C6 unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 1053-1214) antibodyA2M 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 1216-1467) antibodyA2M 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 1-1474) antibodyA2M 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 641-730) antibodyA2M 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2B5 unconjugated
anti-alpha-2-Macroglobulin (A2M) antibodyA2M 适用: 人 WB, IHC, ELISA, IP, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) antibodyA2M 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) antibodyA2M 适用: 人, Pig, 兔, 犬 IHC, ELISA, IP, IEP, IHC (p) 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
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别名
- A2M
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背景
- The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified.,A2M;A2MD;CPAMD5;FWP007;S863-7,Cell Biology & Developmental Biology,Ubiquitin,Cardiovascular,Blood,Serum Proteins,A2M
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分子量
- 163kDa
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基因ID
- 2
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UniProt
- P01023
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途径
- Lipid Metabolism
抗原
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