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alpha Actinin 4 抗体

This 兔 单克隆 anti-alpha Actinin 4 antibody specifically detects alpha Actinin 4 in WB, IF 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN7265399
发货至: 中国
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Quick Overview for alpha Actinin 4 抗体 (ABIN7265399)

抗原

See all alpha Actinin 4 (ACTN4) 抗体
alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

适用

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宿主

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克隆类型

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单克隆

标记

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This alpha Actinin 4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 原理

    α-Actinin-4 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human alpha-Actinin-4

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

    别名

    ACTN4

    背景

    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008],ACTININ-4, FSGS, FSGS1,Cancer,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Extracellular Matrix,Immunology & Inflammation,Invasion and Metastasis,RNA Binding,Signal Transduction,T Cell Receptor Signaling Pathway,ACTN4

    分子量

    105kDa

    基因ID

    81

    UniProt

    O43707

    途径

    Proton Transport
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