ASCL1 抗体 (AA 77-236)
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北京 101111
Quick Overview for ASCL1 抗体 (AA 77-236) (ABIN7265373)
抗原
See all ASCL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 77-236
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原理
- AscL1 Rabbit pAb
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序列
- GGHKSAPKQV KRQRSSSPEL MRCKRRLNFS GFGYSLPQQQ PAAVARRNER ERNRVKLVNL GFATLREHVP NGAANKKMSK VETLRSAVEY IRALQQLLDE HDAVSAAFQA GVLSPTISPN YSNDLNSMAG SPVSSYSSDE GSYDPLSPEE QELLDFTNWF
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 77-236 of human AscL1 (NP_004307.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
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别名
- AscL1
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背景
- This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.,ASCL1,ASH1,HASH1,MASH1,bHLHa46,AscL1,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,AscL1
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分子量
- 25kDa
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基因ID
- 429
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UniProt
- P50553
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途径
- Dopaminergic Neurogenesis
抗原
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