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ABI1 抗体 (AA 180-230)

This anti-ABI1 antibody is a 兔 多克隆 antibody detecting ABI1 in WB 和 IHC. Suitable for 人.
产品编号 ABIN7265359
发货至: 中国

Quick Overview for ABI1 抗体 (AA 180-230) (ABIN7265359)

抗原

See all ABI1 抗体
ABI1 (Abl-Interactor 1 (ABI1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ABI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 180-230

    原理

    ABI1 Rabbit pAb

    序列

    PMSGRGTLGR NTPYKTLEPV KPPTVPNDYM TSPARLGSQH SPGRTASLNQ R

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 180-230 of human ABI1 (NP_001012770).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ABI1 (Abl-Interactor 1 (ABI1))

    别名

    ABI1

    背景

    This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10,11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14.,ABI1,ABI-1,ABLBP4,E3B1,NAP1BP,SSH3BP,SSH3BP1,Signal Transduction,G protein signaling,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Growth factor,EGF,ABI1

    分子量

    35-55kDa

    基因ID

    10006

    UniProt

    Q8IZP0

    途径

    RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling
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