OAS1 抗体 (AA 1-100)
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北京 101111
Quick Overview for OAS1 抗体 (AA 1-100) (ABIN7265323)
抗原
See all OAS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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原理
- OAS1 Rabbit pAb
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序列
- MMDLRNTPAK SLDKFIEDYL LPDTCFRMQI NHAIDIICGF LKERCFRGSS YPVCVSKVVK GGSSGKGTTL RGRSDADLVV FLSPLTTFQD QLNRRGEFIQ
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交叉反应
- 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human OAS1 (NP_002525.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
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别名
- OAS1
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背景
- This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12.,OAS1,E18/E16,IFI-4,OIAS,OIASI,Epigenetics & Nuclear Signaling,OAS1
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分子量
- 41kDa/43kDa/46kDa/47kDa
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基因ID
- 4938
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UniProt
- P00973
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途径
- Hepatitis C
抗原
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