MAPT 抗体
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北京 101111
Quick Overview for MAPT 抗体 (ABIN7233074)
抗原
See all MAPT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Tau Mouse Monoclonal Antibody
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特异性
- This antibody recognizes human, mouse, and rat Tau.
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交叉反应
- 人, 小鼠, 大鼠
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免疫原
- Full-length recombinant human Tau441 (2N4R) P301S mutant protein pre-formed fibrils. In humans, mutation P301S gives rise to early-onset dementia.
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anti-Microtubule-Associated Protein tau (MAPT) (pSer262) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pThr212) antibodyMAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer235) antibodyMAPT 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (AA 1-100) antibodyMAPT 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (AA 130-386) antibodyMAPT 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (AA 34-368) antibodyMAPT 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pThr181) antibodyMAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pThr205) antibodyMAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer404) antibodyMAPT 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein tau (MAPT) (pSer396) antibodyMAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Immunoblotting: use at 1-5 μg/mL. A band of ~45.8 kDa is detected.
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, 0.09 % sodium azide, 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- This product is stable for at least one (1) year at -20°C.
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- MAPT (Microtubule-Associated Protein tau (MAPT))
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别名
- MAPT
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背景
- Microtubule-associated protein tau,Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity (PubMed:21985311). The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both (PubMed:21985311, PubMed:32961270). Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. {PubMed:21985311, PubMed:32961270}.,Cytoplasm, cytosol, Cell membrane, Cytoplasm, cytoskeleton, Cell projection, axon, Cell projection, dendrite, Secreted,Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau
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UniProt
- P10636
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途径
- MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
抗原
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