Immunoblotting: use at 1 μg/mL. Immunohistochemistry: use at 10 μg/mL. These are recommended concentrations. Endusers should determine optimal concentrations for their applications. Positive control: Whole cell lysate from HL60 cells.
限制
仅限研究用
状态
Liquid
溶解方式
Dilute in PBS or medium which is identical to that used in the assay system.
浓度
Lot specific
缓冲液
PBS, pH 7.4
储存条件
-20 °C
储存方法
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
Caspase-13,Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.,Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain-containing adapter molecules and members of the caspase family of proteases. Caspase-13 or ERICE (Evolutionarily Related Interleukin-1 Converting Enzyme) was recently described. When activated by caspase-8, caspase-13 induces apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.,CASP-13, EC 3.4.22.-, Evolutionary related interleukin-1-beta-converting enzyme, ERICE [Cleaved into: Caspase-13 subunit 1, Caspase-13 subunit 2]