YBX1 抗体 (pSer102)
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北京 101111
Quick Overview for YBX1 抗体 (pSer102) (ABIN7222816)
抗原
See all YBX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer102
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原理
- YB-1 (phospho Ser102) Polyclonal Antibody
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特异性
- Phospho-YB-1 (S102) Polyclonal Antibody detects endogenous levels of YB-1 protein only when phosphorylated at S102.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human YB-1 Phospho-Ser102
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- YBX1 (Y Box Binding Protein 1 (YBX1))
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别名
- YB-1
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背景
- Rabbit Anti-YB-1 (phospho Ser102) Polyclonal Antibody,YBX1, NSEP1, YB1, Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A, CBF-A, DNA-binding protein B, DBPB, Enhancer factor I subunit A, EFI-A, Y-box transcription factor, Y-box-binding protein 1, YB-,YBX1 encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. YBX1 may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of YBX1 are found on multiple chromosomes.,Nuclease-sensitive element-binding protein 1
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分子量
- observerd band 36kDa
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基因ID
- 4904
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UniProt
- P67809
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途径
- Regulation of Muscle Cell Differentiation
抗原
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