TSEN2 抗体
Quick Overview for TSEN2 抗体 (ABIN7231306)
抗原
See all TSEN2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SEN2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of SEN2 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human SEN2 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
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别名
- SEN2
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背景
- Rabbit Anti-SEN2 Polyclonal Antibody,tRNA-splicing endonuclease subunit Sen2, tRNA-intron endonuclease Sen2, HsSen2,TSEN2 (TRNA Splicing Endonuclease Subunit 2) is a Protein Coding gene. Diseases associated with TSEN2 include Pontocerebellar Hypoplasia Type 2B and Pontocerebellar Hypoplasia, Type 2E. Among its related pathways are Gene Expression and tRNA processing. TSEN2 encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in TSEN2 have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for TSEN2.,SEN2
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分子量
- observerd band 51kDa
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基因ID
- 80746
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UniProt
- Q8NCE0
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途径
- Nuclear Receptor Transcription Pathway, Regulation of Lipid Metabolism by PPARalpha
抗原
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