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TXNRD1 抗体

This 兔 多克隆 antibody specifically detects TXNRD1 in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7231934
发货至: 中国
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Quick Overview for TXNRD1 抗体 (ABIN7231934)

抗原

See all TXNRD1 抗体
TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

适用

人, 小鼠, 大鼠

宿主

  • 54
  • 5
  • 1

克隆类型

  • 37
  • 23
多克隆

标记

  • 25
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TXNRD1 antibody is un-conjugated

应用范围

  • 49
  • 20
  • 15
  • 15
  • 15
  • 15
  • 13
  • 13
  • 12
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • 原理

    Rabbit Anti-TRXR1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of TRXR1 protein

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human TRXR1 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

    别名

    TRXR1

    背景

    Thioredoxin reductase 1, cytoplasmic, TR, Gene associated with retinoic and interferon-induced mortality 12 protein, GRIM-12, Gene associated with retinoic and IFN-induced mortality 12 protein, KM-102-derived reductase-like factor, Thioredoxin reductase TR1Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

    分子量

    71kD

    基因ID

    7296

    UniProt

    Q16881

    途径

    Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
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