TAB3 抗体
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北京 101111
Quick Overview for TAB3 抗体 (ABIN7231676)
抗原
See all TAB3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-TAB3 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of TAB3 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human TAB3 protein
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亚型
- IgG
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anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) antibody
TAB3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (AA 361-712) antibodyTAB3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) antibodyTAB3 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) antibodyTAB3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2680 unconjugated Recombinant Antibody
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (AA 70-656) antibodyTAB3 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (Internal Region) antibodyVerified TAB3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (AA 50-100) antibodyTAB3 适用: 人, 小鼠, 犬, 小鸡, Cow, Opossum WB 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (Internal Region) antibodyTAB3 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) antibodyTAB3 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (AA 600-650) antibodyTAB3 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
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别名
- TAB3
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背景
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NF-kappa-B-activating protein 1, TAK1-binding protein 3, TAB-3, TGF-beta-activated kinase 1-binding protein 3The product of TAB3 (TGF-Beta Activated Kinase 1 And MAP3K7 Binding Protein 3) functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
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分子量
- 78kD
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基因ID
- 257397
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UniProt
- Q8N5C8
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途径
- TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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