SYN1 抗体 (pSer553)
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Quick Overview for SYN1 抗体 (pSer553) (ABIN7226768)
抗原
See all SYN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer553
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原理
- Synapsin-1 (phospho Ser553) Polyclonal Antibody
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特异性
- Phospho-Synapsin-1 (S553) Polyclonal Antibody detects endogenous levels of Synapsin-1 around the phosphorylation site of S553 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Synapsin-1 Phospho-Ser553
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SYN1 (Synapsin I (SYN1))
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别名
- Synapsin-1
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背景
- Rabbit Anti-Synapsin-1 (phospho Ser553) Polyclonal Antibody,SYN1 (synapsin I) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in SYN1 may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.,Synapsin-1
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分子量
- observerd band 75kDa
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基因ID
- 6853
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UniProt
- P17600
抗原
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