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Ret Proto-Oncogene 抗体 (AA 711-756) (Cy7)

This anti-Ret Proto-Oncogene antibody is a 兔 多克隆 antibody detecting Ret Proto-Oncogene in WB, IF (cc) 和 IF (p). Suitable for 大鼠.
产品编号 ABIN716657
发货至: 中国

Quick Overview for Ret Proto-Oncogene 抗体 (AA 711-756) (Cy7) (ABIN716657)

抗原

See all Ret Proto-Oncogene (RET) 抗体
Ret Proto-Oncogene (RET)

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This Ret Proto-Oncogene antibody is conjugated to Cy7

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 711-756

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Ret/HSCR1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Ret Proto-Oncogene (RET)

    别名

    Ret

    背景

    Synonyms: C ret, Cadherin family member 12, CDHF 12, CDHF12, ELKS Fusion gene, HSCR 1, HSCR1, Hydroxyaryl protein kinase, MEN2A, MEN2B, MTC 1, MTC1, Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Oncogene RET, Proto oncogene tyrosine protein kinase receptor ret, Proto-oncogene c-Ret, Proto-oncogene tyrosine-protein kinase receptor ret, PTC, RET, RET ELE1, Ret Proto oncogene, RET transforming sequence, RET_HUMAN, RET51.

    Background: This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008].

    基因ID

    5979

    途径

    RTK signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
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