SYK 抗体 (pTyr348)
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北京 101111
Quick Overview for SYK 抗体 (pTyr348) (ABIN7231610)
抗原
See all SYK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr348
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原理
- SYK (Phospho-Tyr348) Polyclonal Antibody
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特异性
- This antibody detects endogenous levels of SYK when Phospho occurs at Tyr348
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human SYK (Phospho-Tyr348) Antibody protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SYK (Spleen tyrosine Kinase (SYK))
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别名
- SYK
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背景
- Rabbit Anti-SYK (Phospho-Tyr348) Polyclonal Antibody,Tyrosine-protein kinase SYK, Spleen tyrosine kinase, p72-Syk,SYK (Spleen Associated Tyrosine Kinase) is a Protein Coding gene. Diseases associated with SYK include Hantavirus Pulmonary Syndrome and Mycobacterium Abscessus. Among its related pathways are p70S6K Signaling and RET signaling. SYK encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,SYK
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分子量
- observerd band 82kDa
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基因ID
- 6850
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UniProt
- P43405
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途径
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
抗原
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