S1PR1 抗体 (AA 20-100)
Quick Overview for S1PR1 抗体 (AA 20-100) (ABIN7220120)
抗原
See all S1PR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-100
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原理
- EDG-1 Polyclonal Antibody
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特异性
- EDG-1 Polyclonal Antibody detects endogenous levels of EDG-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human EDG-1 at AA range: 20-100
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
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别名
- EDG-1
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背景
- Rabbit Anti-EDG-1 Polyclonal Antibody,S1PR1, CHEDG1, EDG1, Sphingosine 1-phosphate receptor 1, S1P receptor 1, S1P1, Endothelial differentiation G-protein coupled receptor 1, Sphingosine 1-phosphate receptor Edg-1, S1P receptor Edg-1, CD antigen CD363,The sphingosine-1-phosphate receptor 1 encoded by S1PR1 is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.,Sphingosine 1-phosphate receptor 1
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分子量
- observerd band 43kDa
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基因ID
- 1901
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UniProt
- P21453
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途径
- Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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