STAT5A 抗体 (pSer780)
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北京 101111
Quick Overview for STAT5A 抗体 (pSer780) (ABIN7224518)
抗原
See all STAT5A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer780
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原理
- Stat5a (phospho Ser780) Polyclonal Antibody
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特异性
- Phospho-Stat5a (S780) Polyclonal Antibody detects endogenous levels of Stat5a protein only when phosphorylated at S780.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Stat5a Phospho-Ser780
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亚型
- IgG
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anti-Signal Transducer and Activator of Transcription 5A (STAT5A) antibody
STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 6E5 unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 583-794) antibodySTAT5A 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6D4 unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 1-794) antibodySTAT5A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 635-794) antibodySTAT5A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) antibodyKD Validated STAT5A 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB1920 unconjugated Recombinant Antibody
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 1-104) antibodySTAT5A 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1B12 unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pTyr694) antibodySTAT5A 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pSer780) antibodySTAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pTyr694) antibodySTAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (C-Term) antibodySTAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IP (2-5 μg/mg lysate). ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
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别名
- Stat5a
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背景
- Rabbit Anti-Stat5a (phospho Ser780) Polyclonal Antibody,STAT5A, STAT5, Signal transducer and activator of transcription 5A,The protein encoded by STAT5A (signal transducer and activator of transcription 5A) is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of STAT5A is found to induce the expression of BCL2L1/BCL-X (L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for STAT5A.,Signal transducer and activator of transcription 5A
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分子量
- observerd band 91kDa
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基因ID
- 6776
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UniProt
- P42229
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途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
抗原
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