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SIGLEC7 抗体 (Internal Region)

This 兔 多克隆 anti-SIGLEC7 antibody specifically detects SIGLEC7 in WB, ELISA 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7218098
发货至: 中国
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Quick Overview for SIGLEC7 抗体 (Internal Region) (ABIN7218098)

抗原

See all SIGLEC7 抗体
SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

适用

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宿主

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克隆类型

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多克隆

标记

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This SIGLEC7 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Internal Region

    原理

    CD328 Polyclonal Antibody

    特异性

    CD328 Polyclonal Antibody detects endogenous levels of CD328 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human CD328

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

    别名

    CD328

    背景

    Rabbit Anti-CD328 Polyclonal Antibody,SIGLEC7, AIRM1, Sialic acid-binding Ig-like lectin 7, Siglec-7, Adhesion inhibitory receptor molecule 1, AIRM-1, CDw328, D-siglec, QA79 membrane protein, p75, CD328,Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).,Sialic acid-binding Ig-like lectin 7

    分子量

    observerd band 51kDa

    基因ID

    27036

    UniProt

    Q9Y286
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