SGOL2 抗体 (AA 650-730)
This anti-SGOL2 antibody is a 兔 多克隆 antibody detecting SGOL2 in ELISA 和 IHC (p). Suitable for 人.
Quick Overview for SGOL2 抗体 (AA 650-730) (ABIN7219846)
抗原
See all SGOL2 抗体
SGOL2
(Shugoshin-Like 2 (SGOL2))
适用
人
宿主
兔
克隆类型
多克隆
标记
This SGOL2 antibody is un-conjugated
应用范围
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- AA 650-730
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原理
- Sgo2 Polyclonal Antibody
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特异性
- Sgo2 Polyclonal Antibody detects endogenous levels of Sgo2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Sgo2 at AA range: 650-730
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亚型
- IgG
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anti-Shugoshin-Like 2 (SGOL2) (AA 391-419) antibody
SGOL2 适用: 人 WB 宿主: 兔 Polyclonal RB42663 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SGOL2 (Shugoshin-Like 2 (SGOL2))
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别名
- Sgo2
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背景
- Rabbit Anti-Sgo2 Polyclonal Antibody,SGOL2, Shugoshin-like 2, Shugoshin-2, Sgo2, Tripin,Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.,Shugoshin-like 2
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基因ID
- 151246
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UniProt
- Q562F6
抗原
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