Rhodopsin 抗体 (pSer334)
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Quick Overview for Rhodopsin 抗体 (pSer334) (ABIN7224020)
抗原
See all Rhodopsin (RHO) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer334
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原理
- Rhodopsin (phospho Ser334) Polyclonal Antibody
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特异性
- Phospho-Rhodopsin (S334) Polyclonal Antibody detects endogenous levels of Rhodopsin protein only when phosphorylated at S334.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Rhodopsin Phospho-Ser334
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Rhodopsin (RHO)
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别名
- Rhodopsin
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物质类
- Chemical
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背景
- Rabbit Anti-Rhodopsin (phospho Ser334) Polyclonal Antibody,RHO, OPN2, Rhodopsin, Opsin-2,Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form, which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in RHO (rhodopsin) are also one of the causes of congenital stationary night blindness.,Rhodopsin
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基因ID
- 6010
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UniProt
- P08100
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途径
- WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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